Supplement Review - Infinite Labs: JUGGERNAUT

By Robbie Durand, M.A.
Senior Web Editor

Definition: A juggernaut is a term used to describe a literal or metaphorical force regarded as unstoppable. Infinite Labs had that mentality in mind when they created their new pre-workout formula, JUGGERNAUT™- an explosive pre-workout supplement engineered for any athlete, especially the bodybuilder, striving to build muscle.

Energy drinks may only increase perceived energy levels. Owing to their high sodium and sugar content, and other factors, consumption of energy drinks may actually lead to a contraction (shrinkage) of muscle cells by causing them to lose water. This directly antagonizes your muscle-building efforts in the gym. Let's face it: if you are not motivated to throw some weight on the bar, you are not going to build muscle.

JUGGERNAUT™ is equipped with a revolutionary, one-of-a kind Glyco-Core Plasma Expander that enhances muscle pumps. This plasma expander prevents dehydration, increases endurance, prevents fatigue, and is the perfect complement to the Hypertrophic Myovascular Expansion Complex™ (H.M.E.C.).

Glyco-Core supplies the highest-yielding glycerol load available on the market today. JUGGERNAUT™ is an all-in-one, pre-workout supplement that stimulates muscle fiber growth, which provides you with the drive for explosive power, reduces fatigue and enhances muscle pumps- while providing the user with intense mental focus.

The ingredients in JUGGERNAUT™ were chosen by Infinite Labs' research and development scientists and are based on human, animal and in vitro (outside of the living organism) studies published in peer-reviewed scientific journals. Such studies may be found in databases provided by the National Center for Biotechnology Information. JUGGERNAUT™ is sugar-free, fat-free and low-sodium.

JUGGERNAUT^TM Ingredients

Intense Nitric Oxide Initiating Complex™

Blood vessels are like tiny garden hoses lined with muscle cells that are smooth in appearance. When the smooth muscle lining relaxes, blood vessel diameter increases. Known as vasodilation, this increases blood flow. Nitric Oxide (NO) is a key vasodilator produced in the body from the amino acid arginine. The body's preferred source of arginine for NO production is citrulline. Arginase is an enzyme that breaks down arginine, thereby limiting the production of NO. Norvaline is a natural inhibitor of arginase. Vitamins B-12 and folic acid are co-factors for enzymes involved in NO production. Guanidinopropionic acid is an insulin-sensitizer used by athletes to promote muscle cell volumization. It may also regulate appetite.

Glyco-Core™

Glyco-Core™ increases the water-carrying capacity and volume of plasma, thereby supporting heavier workloads and enhancing vascularity (more prominent veins) and muscularity (more muscle fullness, definition and hardness).

As glycerol draws water into the plasma, creatine draws water into the muscle cell to promote volume-induced anabolism and, over the long term, muscle hypertrophy. Glycerol (1,2,3-propanetriol) has been used to induce hyperhydration in an attempt to offset the deleterious effects of dehydration during long-term aerobic exercise. When glycerol is consumed orally, it is absorbed rapidly, primarily in the small intestine. It is reported to be distributed evenly among all fluid compartments, and promotes hyperhydration by inducing an osmotic gradient. When glycerol is consumed, the plasma glycerol concentration increases in proportion to the dose ingested, thus, without supplemental glycerol ingestion, there will be a decrease in the osmotic gradient- resulting in a loss of hyperhydration.¹

JUGGERNAUT's™ high content of glycerol contributes to its enhanced plasma volume effect and greater muscle pumps. JUGGERNAUT™ also contains chromium, cinnamon, glucose polymers and magnesium support insulin action for maximum creatine uptake. Acting as a buffer of two-carbon acetyl groups in muscle fibers, carnitine sustains muscle force levels in the face of fatigue.

Hypertrophic Myovascular Expansion Complex™

JUGGERNAUT™ is the industry-leading muscular and plasma expansion supplement. These complexes work seamlessly across the muscle cell, with intracellular and vascular spaces providing entire-muscle support of volume, anabolism and hypertrophy. Several studies found that independent of hormone influence or substrate influence, decreased cell volume (cell shrinking) leads to cellular catabolism or protein breakdown, while increased cell volume (cell swelling) leads to anabolism or protein synthesis.^2,3

Decreased body water and intracellular nutrients can lead to cell shrinking and as we now know, increased muscle protein breakdown. Basically, cell swelling or shrinking acted as a 'second messenger' to tell the cell what to do about protein synthesis. The hormones tell the cell to swell or shrink, and it is this swelling or shrinking- not the hormone's action- that leads to changes in protein metabolism. Additionally, a previous research study found that during intense resistance exercise, dehydration was found to blunt plasma testosterone responses to exercise.⁴ Taking JUGGERNAUT™ pre-exercise enhances cell volume and hydration, which promotes an anabolic state.

ProGrow Whey Complex™

JUGGERNAUT™ provides 3 grams of essential and non-essential amino acids, more than enough to trigger a net muscle protein gain (the essential element of muscle hypertrophy) following resistance exercise. A clinical study recently published in the Journal of Strength and Conditioning Research reported excellent findings with a pre/post-workout drink for those training to build a bigger, leaner body. The results were similar to a 2006 study that demonstrated when essential amino acids (EAA) were administered to a group of lifters during four weeks of intense weight training, testosterone levels were enhanced in conjunction with reduced muscle breakdown. The group not receiving EEA had a drop in testosterone levels after four weeks, suggesting EEA are effective for attenuating muscle strength loss during initial high-volume stress, possibly by reducing muscle damage by maintaining an anabolic environment.

Reducing cortisol is an effective way to enhance muscle recovery and growth. This most recent study showed nearly a 50 percent reduction post-exercise muscle damage with a 6-gram dose of EAA. BCAAs are both anabolic and anti-catabolic because of their ability to significantly increase protein synthesis, facilitate the release of hormones as growth hormone (GH), IGF-1 and insulin, and help maintain a favorable testosterone-to-cortisol ratio.^5,6

The JUGGERNAUT™ formula is a 'tool kit' of ingredients that are at a premium in today's world, because of its broad spectrum of energizing and volumizing properties. Circumstances are said to be creatures of the mind. JUGGERNAUT™ enables you to bring mind and muscle to life, to create the greatest possible bodybuilding circumstances for your workout.

The ingredient complexes found in JUGGERNAUT™ are exclusive to Infinite Labs. Glyco-Core™ gives JUGGERNAUT™ the highest glycerol load on the market. ProGrow Whey Complex™ provides 3 grams of protein, whereas many other pre-workout formulas contain no protein. One of the best times to ingest protein is pre-workout. This is thought to be due to the increase in muscle blood flow during exercise, which helps 'push' amino acids provided by digested protein into muscle cells.

JUGGERNAUT™ contains only 8.5 grams of carbohydrates and 49 milligrams of sodium per serving. In contrast, a leading energy drink contains 28 grams of carbohydrates (26 grams of sugar) and 214 milligrams of sodium per serving. Also, energy drinks like those found at most convenience stores do not contain the ingredient complexes that are exclusive to the JUGGERNAUT™ formula.

• Juggernaut is scientifically engineered to…

• Increase Lean Mass

• Stimulate Muscle Fiber Growth

• Provide Explosive Power

• Prolong Endurance

• Enhance Mental Focus

• Significantly Reduce Fatigue

  For more information about Infinite Labs products, please go to www.musculardevelopmentstore.com/infinite-labs.html

  References:

  1. Nelson JL, Robergs RA. Exploring the potential ergogenic effects of glycerol hyperhydration. Sports Med, 2007;37(11):981-1000. Review.
  2. Deiter Haussinger and Florian Lang. Cell volume in the regulation of hepatic function: a mechanism of metabolic control. Biochemica et Biophysica Acta, 1991; 1071: 331-350.
  3. Barbera Stoll, Wolfgang Gerok, Florian Lang, and Dieter Haussinger. Liver cell volume and protein synthesis. Biochemical Journal, 1992; 287: 217-222.
  4. Judelson DA, Maresh CM, Yamamoto LM, Farrell MJ, Armstrong LE, Kraemer WJ, Volek JS, Spiering BA, Casa DJ, Anderson JM. Effect of hydration state on resistance exercise-induced endocrine markers of anabolism, catabolism, and metabolism. J Appl Physiol, 2008 Sep;105(3):816-24. Epub 2008.
  5. Tipton KD, Rasmussen BB, Miller SL, Wolf SE, Owens-Stovall SK, Petrini BE, Wolfe RR. Timing of amino acid-carbohydrate ingestion alters anabolic response of muscle to resistance exercise. Am J Physiol Endocrinol Metab, 281: E197-E206, 2001.
  6. Tipton KD, Elliott TA, Cree MG, Aarsland AA, Sanford AP, Wolfe RR. Stimulation of net muscle protein synthesis by whey protein ingestion before and after exercise. Am J Physiol Endocrinol Metab, 2007 Jan;292(1):E71-6.