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Nutrex: LIPO-6 Black Ultra Concentrate: The World's First Intelligent Fat Destroyer

By Robbie Durand, M.A.
Senior Science Editor

Nutrex's new LIPO-6 Black Ultra Concentrate is the first revolutionary "intelligent" fat burner, which has a three-way fat burning system. LIPO-6 Black Ultra Concentrate is the greatest product that Nutrex researchers have ever invented, and it signals the beginning of a new era in fat-burning supplementation. It's the world's first one-pill-only fat destroyer that combines receptor cleansing and re-programming agents with an ultra-concentrated fat-destroying complex.

First, LIPO-6 Black Ultra Concentrate has a receptor-cleansing formula. Regular use of fat burners clogs and desensitizes adrenergic receptor sites on the cell's surface, leading to a loss in product effectiveness, reduced fat-loss results and diminished stimulant response. It has been well-established that the now-banned ephedrine had potent receptor downregulation effects, which explains why it worked well in the beginning but the effects soon wore off.1

LIPO-6 Black Ultra Concentrate cleanses receptors with Phenylpropanoids. By cleansing the receptor site on the cell's surface, this allows LIPO-6 Black Ultra Concentrate set the stage for proper cell-to-cell communication. Next step is the reprogramming of receptors with monoterpenes, which reprogram miswritten information deep within the cell's memory, thus creating a refreshed receptor.

Lastly, LIPO-6 Black Ultra Concentrate hits the refreshed receptor with an ultra-concentrated "one pill only" fat-destroying complex. This results in maximum fat loss due to the heightened response of the refreshed receptor.

Five Ultra-Concentrated Fat Burning Ingredients in One Capsule

Unlike most fat burners, which require three to five capsules per day, LIPO-6 Black Ultra Concentrate requires only one capsule in the morning and one in the afternoon! That's it! This is an ultra-concentrated product that relies on just five ultra-pure and super-concentrated fat-burning compounds. It's so strong that you will never need to take more than one pill. LIPO-6 Black Ultra Concentrate contains the unique blend of Caffeine Anhydrous, Methylhexaneamine, Advantra Z, Citrus Aurantium (60 percent Synephrine), Yohimbine HCL and 3,5 Diiodo-L-Thyronine.

Caffeine Anhydrous

Caffeine provides a variety of enhancements for the neuromuscular system including increases in the secretion of catecholamines, which enhance fat burning.2-4 Caffeine, with its capacity to optimize skeletal muscle contraction from augmented neuromuscular transmission, has demonstrated its ability to enhance strength gains and increase work volume- which is essential when calories are low.5,6 While allowing you to work harder, caffeine also boosts your metabolism, assisting in body fat loss while recruiting lean body mass.7, 8 Caffeine also improves mental alertness and mood function, optimizing your level of focus through your workouts or fatigue-battling tasks. By providing caffeine in its anhydrous form, you're getting a more pure form for maximal potency.

Synephrine

Synephrine activates beta-3 adrenoreceptors and therefore, displays a lipolytic and thermogenetic capacity as it boosts norepinephrine levels.9 By consuming synephrine prior to workouts, you enhance fat breakdown (whilesparing muscle) with subsequent utilization of body fat for energy.10 Synephrine has demonstrated its efficacyas an ephedra alternative for revving your metabolism, without altering heart rate or blood pressure.11,12Synephrine further acts as a powerful appetite suppressant, curbing hunger pains during a calorie-restricted diet.

Yohimbine

Yohimbine is just right for the thermogenetic concoction in LIPO-6 Black Ultra Concentrate to help induce lipolysis. Yohimbine is a naturally-occurring compound that some researchers suggest has a "drug-like" effect on fat metabolism. Yohimbine is a highly unusual compound, as it is a natural alpha-2 antagonist that promotes sympathetic activity by central as well as peripheral mechanisms to promote fat loss. Furthermore, yohimbine induces excitatory effects, improving elements of cognitive function andprimarily alertness.9

Yohimbine is great for losing fat in the glutes, hips, and thighs- as fat cells located around the hips and thighs characteristically contain very few beta-receptors and respond poorly to catecholamine release that is induced by exercise and beta-stimulants.13 However, these lower-body fat cells contain a lot of alpha adrenoreceptors.14 Research has shown that yohimbine administration increases lipolysis by antagonizing the anti-lipolytic activity of alpha-2 adrenoreceptors on fat cells.13 This blockade of the alpha-receptors by yohimbine results in increased fat mobilization from these stubborn cells, and increases in blood FFA concentrations during and after exercise to ensure a high rate of fat metabolism.

3,5-DIIODOTHYRONINE are T3 metabolites, which have clinically been shown to raise resting metabolic rate. By manipulating the influx of nutrients into the "cellular powerhouse," you turn the mitochondria into a fat-burning furnace. LIPO-6 Black Ultra Concentrate truly shines by increasing the activity of UCP and causes your body to burn more fatty acids as an energy source. LIPO-6 Black Ultra Concentrate exerts a direct enhancement of metabolic rate via an increase in oxygen consumption, body temperature, and resting metabolic rate (the rate at which your body burns calories at rest). LIPO-6 Black Ultra Concentrate exerts small increases in T3, which increases uncoupling protein 3 (UCP3) found in muscle.15,16 LIPO-6 Black Ultra Concentrate causes nutrient-partitioning effects; it causes small increases in T3, resulting in increased protein synthesis for increases in lean muscle mass.

Methylhexaneamine

Methylhexaneamine is an aliphatic amine, with good peripheral adrenergic activity that stimulates the sympathetic nervous system and promotes mental stimulation, mood enhancement, energy production, dilated bronchioles (to ease breathing during workouts), weight loss, and appetite suppression. Methylhexaneamine's ability to increase mood comes from its direct effect on the cerebral cortex of the brain. Methylhexaneamine is great for dieting, as it promotes a positive mood enhancement and enhances energy.

Underground Strength Fat-Destroyer: Beyond Extreme Formula

  • Five-Prong Approach to Annihilate Body Fat
  • Contains a Powerful Thyronine for Hyper-Active Fat Metabolization
  • Contains Yohimbine for Maximum Fat Release
  • Generates Increased Body Heat to Melt Away Fat Deposits
  • Complete Liquid Dispersion for Maximum Potency

    • For more information about Nutrex products, please visit www.musculardevelopmentstore.com/nutrex-research-inc-.html.

    References:

    1. Williams BR, Barber R, Clark RB. Kinetic analysis of agonist-induced down-regulation of the beta(2)-adrenergic receptor in BEAS-2B cells reveals high- and low-affinity components. Mol Pharmacol, 2000 Aug;58(2):421-30.
    2. Costill DL, Dalsky GP, Fink WJ. Effects of caffeine ingestion on metabolism and exercise performance. Med Sci Sports Exerc, 1978, 10:155-158.
    3. Graham TE. Caffeine and exercise: Metabolism, endurance, and performance. Sports Med, 2001, 31:786-807.
    4. Ivy JL, Costill DL, Fink WJ, Lower RW. Influence of caffeine and carbohydrate feedings on endurance performance. Med Sci Sports Exerc, 1979, 11:6-11.
    5. Kalmar JM, and Cafarelli E. Effects of caffeine on neuromuscular function. J Appl Physiol, 1999, 87:801-808.
    6. Beck TW, Housh TJ, Schmidt RJ, Johnson GO, Housh DJ, Coburn JW and Malek MH. The acute effects of a caffeine-containing supplement on strength, muscular endurance, and anaerobic capabilities. J Strength Cond Res, 2006, 20(3):506-510.
    7. Acheson KJ, Zahorska-Markiewicz B, Pittet P, Anantharaman K and Jequier E. Caffeine and coffee: their influence on metabolic rate and substrate utilization in normal weight and obese individuals. American Journal of Clinical Nutrition, 1980. Vol 33, 989-997.
    8. Dulloo AG, Geissler CA, Horton T, Collins A, Miller DS. Normal caffeine consumption: influence on thermogenesis and daily energy expenditure in lean and postobese human volunteers. Am J Clin Nutr, 1989. 49:44-50.
    9. D'Andrea G, Terrazzino S, Fortin D, Farruggio A, Rinaldi L, Leon A. HLPC electrochemical detection of trace amines in human plasma and platelets and expression of mRNA transcripts of trace amine receptors in circulating leukocytes. Neurosci Lett, 2003, 346:89-92.
    10. Kalman DS, Colker CM, Shi Q, Swain MA. Effects of a weight-loss aid in healthy overweight adults: double-blind, placebo-controlled clinical trials. Curr Ther Res, 2000; 61(4):199-205.
    11. Colker CM, Kalman DS, Torina GC, Perlis T, Street C. Effects of Citrus Aurantium Extract, Caffeine, and St. John''s Wort on body fat loss, lipid levels, and mood states in overweight healthy adults. Curr Ther Res, 1999; 60(3):145-153.